Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700575 | 0.98 | OPRM1 (0.61) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL11880676 | 0.83 | KMT2A (0.49) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL2355874 | 0.81 | GRIN2B (0.60) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9315866 | 0.80 | GRIN2B (0.59) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL11092646 | 0.79 | OPRM1 (0.45) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL18114794 | 0.78 | OPRK1 (1.00) | OPRM1OPRK1OPRD1DRD2DRD3 | |
| SCHEMBL16757238 | 0.77 | SLC6A2 (0.56) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL29118968 | 0.77 | CYP2D6 (0.35) | OPRM1OPRK1OPRD1ALDH1A1HTT | |
| SCHEMBL21047682 | 0.76 | OPRM1 (0.55) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL3154343 | 0.75 | KMT2A (0.55) | OPRM1OPRK1OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289881-A2 | 2-Aminoalkyl-4-benzyl-1-(2H)-phthalazinone derivatives | ASTA Medica Aktiengesellschaft (DE) | 1988-11-09 | — | — | EP | disclosed |