Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700520 | 0.88 | MAPT (0.51) | CYP1A2CYP3A4CYP2C19LTA4HKMT2A | |
| SCHEMBL10696261 | 0.87 | L3MBTL1 (0.53) | CYP1A2CYP3A4CYP2C19LTA4HKMT2A | |
| SCHEMBL21991488 | 0.84 | PTGS2 (0.58) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL15707774 | 0.83 | MAPT (0.63) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL21992620 | 0.80 | PTGS2 (0.54) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL23182535 | 0.78 | CYP1A2 (0.46) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL21991800 | 0.78 | HPGD (0.58) | CYP1A2CYP3A4CYP2C19PTGS2KMT2A | |
| SCHEMBL27561766 | 0.77 | PTGS2 (0.54) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL21992633 | 0.77 | MAOB (0.60) | PTGS2KMT2AATMNPC1ALDH1A1 | |
| SCHEMBL24805957 | 0.75 | PTGS2 (0.49) | HRH3CYP1A2CYP3A4CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |