Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696261 | 0.89 | L3MBTL1 (0.53) | MAPTLTA4HALDH1A1HTTKMT2A | |
| SCHEMBL10698016 | 0.88 | HRH3 (0.53) | MAPTLTA4HALDH1A1HTTKMT2A | |
| SCHEMBL11233455 | 0.83 | MAPT (0.66) | MAPTSMN1; SMN2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL23857640 | 0.79 | MEP1B (0.58) | MAPTSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL10698074 | 0.79 | LMNA (0.56) | MAPTSMN1; SMN2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14566050 | 0.79 | MAPT (0.56) | MAPTSMN1; SMN2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL64783 | 0.75 | KMT2A (0.65) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL9729899 | 0.75 | MAPT (0.59) | MAPTMTNR1AMTNR1BHTTKMT2A | |
| SCHEMBL64222 | 0.74 | KMT2A (0.54) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL64678 | 0.74 | KMT2A (0.54) | MAPTALDH1A1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |