Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696872 | 0.84 | ALDH1A1 (0.63) | ALDH1A1POLBCXCR4HRH3KMT2A | |
| SCHEMBL10701011 | 0.82 | ALDH1A1 (0.51) | ALDH1A1LMNAPOLBCXCR4HRH3 | |
| SCHEMBL3334754 | 0.82 | HRH3 (0.48) | ALDH1A1HRH3HRH4ACHEBACE1 | |
| SCHEMBL1808667 | 0.81 | SIGMAR1 (0.57) | ALDH1A1LMNAPOLBHRH3ACHE | |
| SCHEMBL1046331 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAPOLBCXCR4HRH3 | |
| SCHEMBL13215736 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAPOLBCXCR4HRH3 | |
| SCHEMBL11852 | 0.81 | HRH3 (0.74) | ALDH1A1LMNAPOLBCXCR4HRH3 | |
| SCHEMBL1045984 | 0.79 | ALDH1A1 (0.74) | ALDH1A1LMNAPOLBCXCR4HRH3 | |
| SCHEMBL329323 | 0.79 | HRH3 (0.78) | ALDH1A1LMNAPOLBCXCR4HRH3 | |
| SCHEMBL1045595 | 0.79 | ALDH1A1 (0.74) | ALDH1A1LMNAPOLBCXCR4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |