Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698243 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4EHRH3HRH4POLB | |
| SCHEMBL10701011 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EHRH3HRH4POLB | |
| SCHEMBL3334754 | 0.84 | HRH3 (0.48) | ALDH1A1KDM4EHRH3HRH4MAPT | |
| SCHEMBL1808667 | 0.83 | SIGMAR1 (0.57) | ALDH1A1KDM4ESIGMAR1HRH3POLB | |
| SCHEMBL1429999 | 0.80 | HRH3 (0.49) | ALDH1A1KDM4EHRH3LSSPOLB | |
| SCHEMBL23851111 | 0.80 | ALDH1A1 (0.87) | ALDH1A1KDM4ESIGMAR1HRH3HRH4 | |
| SCHEMBL7937990 | 0.80 | ALDH1A1 (0.95) | ALDH1A1KDM4ESIGMAR1HRH3HRH4 | |
| SCHEMBL1276590 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4ESIGMAR1HRH3HRH4 | |
| Hydrochloric Acid SCHEMBL7281619 | 0.78 | ALDH1A1 (0.91) | ALDH1A1KDM4ESIGMAR1HRH3HRH4 | |
| SCHEMBL11227514 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4ESIGMAR1HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |