Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 5/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543018 | 0.81 | KMO (0.50) | KMOGRM8GRM4GRM6GAA | |
| SCHEMBL639675 | 0.81 | KMO (0.50) | KMOGRM8GRM4GRM6GAA | |
| SCHEMBL465890 | 0.81 | KMO (0.50) | KMOGRM8GRM4GRM6GAA | |
| Water SCHEMBL6282445 | 0.80 | KMO (0.49) | KMOGRM8GRM4GRM6GAA | |
| Hydrochloric Acid SCHEMBL10950905 | 0.80 | KMO (0.49) | KMOGRM8GRM4GRM6GAA | |
| Iodide SCHEMBL10947423 | 0.80 | KMO (0.49) | KMOGRM8GRM4GRM6GAA | |
| Bromide SCHEMBL10946974 | 0.80 | KMO (0.49) | KMOGRM8GRM4GRM6GAA | |
| Hydrochloric Acid SCHEMBL11310889 | 0.80 | KMO (0.49) | KMOGRM8GRM4GRM6GAA | |
| Glutamic Acid SCHEMBL3126271 | 0.73 | GRM8 (0.53) | KMOGRM8GRM4GRM6MAPT | |
| Glutamic Acid SCHEMBL29088693 | 0.72 | GRM8 (0.51) | KMOGRM8GRM4GRM6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769447-A | SUBSTRATES FOR G-GLUTAMYL TRANSFERASE DETERMINATION | BOEHRINGER MANNHEIM GMBH (DE) | 1988-09-06 | — | — | US | disclosed |