Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 7/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.53 |
| ▸ | GRM6 | O15303 | 3/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamic Acid SCHEMBL29088693 | 0.99 | GRM8 (0.51) | GRM8GRM4GRM6GRIK1GRIK2 | |
| D-Glutamate SCHEMBL28889377 | 0.85 | GRM8 (0.49) | GRM8GRM4GRM6GRIK1GRIK2 | |
| Lysine SCHEMBL28327845 | 0.83 | GSR (0.56) | GRM8GRM4GRM6GRIK1GRIK2 | |
| Lysine SCHEMBL28385610 | 0.83 | GSR (0.56) | GRM8GRM4GRM6GRIK1GRIK2 | |
| 4-Nitroaniline SCHEMBL2934316 | 0.82 | ALDH1A1 (0.56) | GRM8GRM4GRM6GRIK1GRIK2 | |
| 4-Nitroaniline SCHEMBL2934312 | 0.82 | ALDH1A1 (0.56) | GRM8GRM4GRM6GRIK1GRIK2 | |
| 4-Nitroaniline SCHEMBL6705231 | 0.82 | GRM8 (0.49) | GRM8GRM4GRM6GRIK1GRIK2 | |
| 4-Nitroaniline SCHEMBL10381907 | 0.82 | GRM8 (0.49) | GRM8GRM4GRM6GRIK1GRIK2 | |
| Lysine SCHEMBL27760108 | 0.82 | GSR (0.54) | GRM8GRM4GRM6GRIK1GRIK2 | |
| Lysine SCHEMBL27760106 | 0.82 | GSR (0.54) | GRM8GRM4GRM6GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9196912-A | — | — | None | — | — | JP | disclosed |
| CN-119320427-A | Stropharia rugoso-annulata umami peptide and screening method and application thereof | 华东师范大学 | 2025-01-17 | — | — | CN | disclosed |
| CN-112961848-B | Novel aminopeptidase and soluble expression method thereof | 中国海洋大学 | 2022-09-09 | — | — | CN | disclosed |
| US-20100197745-A1 | GAMMA-GLUTAMYL TRANSPEPTIDASE INHIBITORS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2010-08-05 | — | — | US | disclosed |
| JP-H09196912-A | ALZHEIMER'S DISEASE DIAGNOSTIC DRUG | TOKYO MET GOV RINSHIYOU IGAKU SOGO KENKYUSHO | 1997-07-31 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197745-A1 | GAMMA-GLUTAMYL TRANSPEPTIDASE INHIBITORS AND METHODS OF USE | GGT1, GSTA1, GLS | GRM8 3917/4885GRM4 3252/4885GRM6 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.