Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698352 | 0.90 | KDM4E (0.59) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL5571188 | 0.80 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL8510279 | 0.80 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL2550199 | 0.80 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL8470561 | 0.79 | WDR5 (0.55) | KDM4EMAOBAOC3ALDH1A1GAA | |
| SCHEMBL585546 | 0.78 | KDM4E (0.68) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL31645913 | 0.78 | KDM4E (0.68) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL30517922 | 0.77 | KDM4E (0.67) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL10932863 | 0.77 | KDM4E (0.71) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 | |
| SCHEMBL13642053 | 0.77 | KDM4E (0.67) | KDM4EMAOBAOC3MRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289349-A1 | Prostaglandins of the F series | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-11-02 | — | — | EP | disclosed |