Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31645913 | 1.00 | KDM4E (0.68) | KDM4EMRGPRX4MAOBAOC3LMNA | |
| SCHEMBL11112064 | 0.87 | KDM4E (0.57) | KDM4EMRGPRX4MAOBAOC3LMNA | |
| SCHEMBL9811742 | 0.85 | KDM4E (0.67) | KDM4EMRGPRX4MAOBAOC3LMNA | |
| SCHEMBL10932863 | 0.85 | KDM4E (0.71) | KDM4EMRGPRX4MAOBAOC3LMNA | |
| SCHEMBL30517922 | 0.85 | KDM4E (0.67) | KDM4EMRGPRX4MAOBAOC3LMNA | |
| SCHEMBL13642053 | 0.85 | KDM4E (0.67) | KDM4EMRGPRX4MAOBAOC3LMNA | |
| SCHEMBL1451309 | 0.84 | KDM4E (0.57) | KDM4EMRGPRX4LMNANR4A2PPARG | |
| SCHEMBL30953672 | 0.84 | KDM4E (0.57) | KDM4EMRGPRX4LMNANR4A2PPARG | |
| SCHEMBL30831879 | 0.83 | SMN1; SMN2 (0.65) | LMNAALOX15NR4A2PPARGPPARA | |
| SCHEMBL1986392 | 0.83 | SMN1; SMN2 (0.65) | LMNAALOX15NR4A2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | claimed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | claimed |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| CN-110143932-B | Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds | 南开大学 | 2022-09-16 | — | — | CN | disclosed |
| US-20220026805-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| WO-2021236395-A1 | CB-0406 CHOLINE SALT | CYMABAY THERAPEUTICS, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021236394-A1 | CB-0406 TROMETHAMINE SALT | CYMABAY THERAPEUTICS, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021221169-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2021-11-04 | — | — | WO | disclosed |
| EP-3560928-B1 | FUSED IMIDAZOLE COMPOUND HAVING INDOLEAMINE 2,3-DIOXYGENASE INHIBITORY ACTIVITY | SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |
| CN-108203438-B | Fused imidazole compounds having indoleamine 2,3-dioxygenase inhibitory activity | 深圳微芯生物科技股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| US-4416687-A | 3,5-Bis (trifluoromethyl)phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0088066-A1 | 3,5-Bis (trifluoromethyl) phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-09-07 | — | — | EP | disclosed |
| US-4138577-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138575-A | 11-Deoxy-16-phenoxy-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138576-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138573-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4126754-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4090862-A | Novel phenoxycarboxylic acid aryloxy(thio)carbonylaminomethyl esters and their use for regulating plant growth | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-23 | — | — | US | disclosed |
| US-4020167-A | COMBATTING NARCOSIS | THE DOW CHEMICAL COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | TRPV4, TRPV1, TRPV2 | KDM4E 2319/4885MRGPRX4 49/4885MAOB 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.