Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470558 | 0.90 | WDR5 (0.56) | WDR5FKBP1APOLBMAOBAOC3 | |
| SCHEMBL6258856 | 0.84 | MRGPRX4 (0.37) | WDR5KDM4ELMNAENPP2 | |
| SCHEMBL10698348 | 0.79 | KDM4E (0.58) | POLBMAOBAOC3GAAKDM4E | |
| SCHEMBL10655455 | 0.78 | WDR5 (0.57) | WDR5FKBP1APOLBMAOBAOC3 | |
| SCHEMBL10655453 | 0.78 | WDR5 (0.57) | WDR5FKBP1APOLBMAOBAOC3 | |
| SCHEMBL9205686 | 0.78 | WDR5 (0.65) | WDR5FKBP1APOLBMAOBAOC3 | |
| SCHEMBL29590819 | 0.76 | WDR5 (0.62) | WDR5FKBP1APOLBMAOBAOC3 | |
| SCHEMBL1308577 | 0.76 | WDR5 (0.62) | WDR5FKBP1APOLBMAOBAOC3 | |
| SCHEMBL29447016 | 0.76 | LMNA (0.64) | WDR5FKBP1APOLBMAOBAOC3 | |
| SCHEMBL523934 | 0.76 | LMNA (0.64) | WDR5FKBP1APOLBMAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889052-A | TOPICAL ADMINISTERING | ALCON LABORATIES, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5698733-A | TOPICAL ADMINISTRATION | ALCON LABORATORIES, INC. (US) | 1997-12-16 | — | — | US | disclosed |