Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | GRM6 | O15303 | 7/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713793 | 0.80 | GRM6 (0.47) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL13673996 | 0.80 | ALOX5 (0.46) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL16996824 | 0.77 | GRM6 (0.52) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL26724795 | 0.75 | ALOX5 (0.40) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL14190044 | 0.75 | GRM6 (0.50) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL26724789 | 0.72 | ALOX5 (0.41) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL10690630 | 0.72 | ALOX5 (0.41) | ALOX5GRM6GRM5ALDH1A1MAPT | |
| SCHEMBL21494935 | 0.71 | GRM6 (0.49) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL13398540 | 0.71 | GRM6 (0.49) | ALOX5GRM6GRM5HPGDALDH1A1 | |
| SCHEMBL10109209 | 0.70 | ALOX5 (0.42) | ALOX5GRM6HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255478-A1 | Tris(substituted hydroxyphenyl-thio)trithioorthoesters | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |