Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713793 | 0.80 | GRM6 (0.47) | GRM6MAPTALDH1A1LMNALIMK1 | |
| SCHEMBL17107090 | 0.77 | ALDH1A1 (0.50) | GRM6MAPTALDH1A1LMNALIMK1 | |
| SCHEMBL10690630 | 0.77 | ALOX5 (0.41) | GRM6MAPTALDH1A1LMNALIMK1 | |
| SCHEMBL26724795 | 0.75 | ALOX5 (0.40) | GRM6MAPTALDH1A1LMNALIMK1 | |
| SCHEMBL16996824 | 0.72 | GRM6 (0.52) | GRM6MAPTALDH1A1LMNALIMK1 | |
| SCHEMBL10698380 | 0.71 | ALOX5 (0.48) | GRM6MAPTALDH1A1LIMK1GRM5 | |
| SCHEMBL13398540 | 0.71 | GRM6 (0.49) | GRM6MAPTALDH1A1LMNAGRM5 | |
| SCHEMBL14190044 | 0.70 | GRM6 (0.50) | GRM6MAPTALDH1A1LMNALIMK1 | |
| SCHEMBL10109209 | 0.70 | ALOX5 (0.42) | GRM6MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL13125888 | 0.68 | GRM6 (0.38) | GRM6MAPTALDH1A1LIMK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781565-A1 | 2-METHYL-AZA-QUINAZOLINES | Bayer Pharma Aktiengesellschaft (DE) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019201848-A1 | 2-METHYL-AZA-QUINAZOLINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-24 | — | — | WO | disclosed |