SCHEMBL10698384

SCHEMBL10698384

C=C(C(=O)O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2976620 0.89 NOTUM (0.34) HPGDSMN1; SMN2
SCHEMBL9423295 0.86 POLB (0.32) HPGDSMN1; SMN2
SCHEMBL4404031 0.86 POLB (0.32) HPGDSMN1; SMN2
SCHEMBL29449329 0.86 POLB (0.32) HPGDSMN1; SMN2
SCHEMBL9497450 0.85 GRM4 (0.30)
SCHEMBL31362249 0.85 LMNA (0.34) HPGDSMN1; SMN2
SCHEMBL9497444 0.85 POLB (0.32) HPGDSMN1; SMN2
SCHEMBL27559360 0.83 GAA (0.36) HPGDSMN1; SMN2
SCHEMBL30704867 0.83 GAA (0.36) HPGDSMN1; SMN2
SCHEMBL25480755 0.83 FFAR4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255047-A1 3-Aryl uraciles and their use as herbicides CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed