SCHEMBL9497450

SCHEMBL9497450

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(C(O)=S)c(Cl)cc2F)c1=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2976620 0.89 NOTUM (0.34) GRM4
SCHEMBL9423295 0.87 POLB (0.32)
SCHEMBL29449329 0.87 POLB (0.32)
SCHEMBL4404031 0.87 POLB (0.32)
SCHEMBL31362249 0.86 LMNA (0.34)
SCHEMBL9497444 0.86 POLB (0.32)
SCHEMBL10698384 0.85 HPGD (0.32)
SCHEMBL10695874 0.85 BCAT1 (0.34) GRM4
SCHEMBL10695876 0.85 BCAT1 (0.34) GRM4
SCHEMBL30704867 0.84 GAA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0344232-B1 3-ARYLURACILS FOR KILLING WEEDS CIBA-GEIGY AG (CH) 1993-03-24 EP claimed
US-5041156-A 3-aryluracils for the control of weeds CIBA-GEIGY CORPORATION (US) 1991-08-20 US claimed
US-5041156-A 3-aryluracils for the control of weeds CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed