Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696376 | 0.88 | POLB (0.43) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10532303 | 0.86 | MAPT (0.45) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10697744 | 0.86 | MAPT (0.41) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10698788 | 0.83 | MAPT (0.55) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10693972 | 0.83 | NPC1 (0.41) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10530680 | 0.78 | POLB (0.41) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10532432 | 0.78 | MAPT (0.43) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10534500 | 0.77 | POLB (0.40) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL10532531 | 0.77 | MAPT (0.40) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL5563212 | 0.77 | RECQL (0.42) | MAPTKMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |