Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377052 | 0.98 | TRPV1 (0.47) | TRPV1PRKCAPTPN1CYP2D6MAPT | |
| SCHEMBL27849907 | 0.98 | TRPV1 (0.47) | TRPV1PRKCAPTPN1CYP2D6MAPT | |
| SCHEMBL3051954 | 0.89 | PRKCA (0.49) | TRPV1PRKCACYP2D6MAPTTP53 | |
| SCHEMBL12611049 | 0.89 | PTPN1 (0.49) | TRPV1PTPN1CYP2D6MAPTLMNA | |
| SCHEMBL12774845 | 0.86 | TRPV1 (0.49) | TRPV1PTPN1SPHK1GPR84FFAR1 | |
| SCHEMBL10698423 | 0.84 | PTPN1 (0.49) | TRPV1PRKCAPTPN1CYP2D6MAPT | |
| SCHEMBL9007930 | 0.84 | TRPV1 (0.50) | TRPV1PRKCAPTPN1MAPTLMNA | |
| SCHEMBL28452236 | 0.81 | MAPT (0.60) | PRKCAMAPTLMNAKDM4EMEN1 | |
| SCHEMBL7612157 | 0.81 | MAPT (0.60) | PRKCAMAPTLMNAKDM4EMEN1 | |
| SCHEMBL28029399 | 0.81 | ABCB1 (0.44) | PTPN1CYP2D6MAPTLMNASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287652-B1 | SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS | LIFE TECHNOLOGIES INC (US) | 1994-01-12 | — | — | EP | claimed |
| US-7635798-B2 | Nucleic acid compositions conferring altered metabolic characteristics | DOW AGROSCIENCES, LLC (US) | 2009-12-22 | — | — | US | disclosed |
| US-20050091708-A1 | Nucleic acid compositions conferring altered metabolic characteristics | DOW AGROSCIENCES LLC | 2005-04-28 | — | — | US | disclosed |
| WO-2003020936-A1 | NUCLEIC ACID COMPOSITIONS CONFERRING ALTERED METABOLIC CHARACTERISTICS | THE DOW CHEMICAL COMPANY (US) | 2003-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050091708-A1 | Nucleic acid compositions conferring altered metabolic characteristics | FADS1, FASN, FADS2 | TRPV1 3009/4885PRKCA 3400/4885PTPN1 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.