Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980027 | 0.89 | PRKCA (0.44) | PRKCAADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL11548207 | 0.87 | PRKCA (0.44) | PRKCAADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL1665609 | 0.87 | PRKCA (0.53) | PRKCAADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL1982633 | 0.85 | PRKCA (0.45) | PRKCAADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL3229513 | 0.85 | PRKCA (0.51) | PRKCAADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL29020020 | 0.85 | PRKCA (0.51) | PRKCAGLS2 | |
| SCHEMBL11654945 | 0.83 | PRKCA (0.49) | PRKCAGLS2 | |
| SCHEMBL9580116 | 0.83 | PRKCA (0.53) | PRKCAGLS2 | |
| SCHEMBL11654951 | 0.83 | PRKCA (0.49) | PRKCAGLS2 | |
| SCHEMBL23016693 | 0.82 | ADRA1D (0.56) | PRKCAADRA1DPTAFRHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284395-A2 | Novel glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |