Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.46 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698104 | 0.88 | LTA4H (0.47) | LTA4HHRH3KCNA5HRH2HRH1 | |
| SCHEMBL10695019 | 0.80 | KDM4E (0.53) | LTA4HHRH3KCNA5KDM4EALDH1A1 | |
| SCHEMBL10696248 | 0.77 | KCNA5 (0.45) | LTA4HHRH3KCNA5HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL10696621 | 0.76 | KCNA5 (0.44) | LTA4HHRH3KCNA5HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL10691702 | 0.76 | KCNA5 (0.48) | LTA4HHRH3KCNA5HRH2HRH1 | |
| SCHEMBL13980797 | 0.73 | LTA4H (0.67) | LTA4HHRH3HRH2HRH1ALDH1A1 | |
| SCHEMBL10191924 | 0.73 | LTA4H (0.67) | LTA4HHRH3HRH2HRH1ALDH1A1 | |
| SCHEMBL14570558 | 0.70 | HRH3 (0.66) | LTA4HHRH3KCNA5HRH2HRH1 | |
| SCHEMBL10696993 | 0.70 | KDM4E (0.54) | LTA4HHRH3KCNA5HRH2HRH1 | |
| SCHEMBL10696548 | 0.70 | MEN1 (0.49) | LTA4HHRH3KCNA5ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |