Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 8/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10696621 | 0.99 | KCNA5 (0.44) | KCNA5LTA4HDRD3DRD2HRH3 | |
| SCHEMBL10697140 | 0.92 | DRD3 (0.51) | KCNA5LTA4HDRD3DRD2LMNA | |
| Hydrochloric Acid SCHEMBL10696092 | 0.91 | DRD3 (0.50) | KCNA5LTA4HDRD3DRD2LMNA | |
| SCHEMBL10696548 | 0.90 | MEN1 (0.49) | KCNA5LTA4HDRD3DRD2HRH3 | |
| Hydrochloric Acid SCHEMBL10696599 | 0.89 | MEN1 (0.48) | KCNA5LTA4HDRD3DRD2HRH3 | |
| SCHEMBL10695039 | 0.83 | OPRM1 (0.39) | DRD3DRD2 | |
| SCHEMBL10693226 | 0.82 | DRD3 (0.45) | DRD3DRD2 | |
| SCHEMBL10697263 | 0.81 | DRD2 (0.47) | DRD3DRD2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10696916 | 0.81 | DRD2 (0.46) | DRD3DRD2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10696100 | 0.79 | KDM4E (0.50) | LTA4HDRD2HRH3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | claimed |