Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150175 | 0.83 | KDM4E (0.42) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL7845387 | 0.83 | ALDH1A1 (0.46) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3812812 | 0.78 | ALDH1A1 (0.43) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL27976888 | 0.78 | ALDH1A1 (0.41) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL15999549 | 0.78 | KDM4E (0.39) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9027382 | 0.78 | KDM4E (0.68) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9168466 | 0.78 | KDM4E (0.46) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL30390219 | 0.78 | KDM4E (0.68) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL8094560 | 0.77 | EPHA2 (0.53) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10516924 | 0.76 | LMNA (0.60) | KDM4ELMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266576-A2 | 1-Tert-alkyl-substituted naphthyridine and quinoline carboxylic acids as antibacterial agents | Bristol-Myers Squibb Company (US) | 1988-05-11 | — | — | EP | disclosed |