Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17219775 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9AGAALMNAHPGD | |
| SCHEMBL31482410 | 0.81 | NFE2L2 (0.56) | SMN1; SMN2RAB9ALMNAALDH1A1MAOB | |
| SCHEMBL701638 | 0.81 | TAS1R3 (0.60) | SMN1; SMN2RAB9ALMNAHPGDMAOB | |
| SCHEMBL701639 | 0.81 | TAS1R3 (0.60) | SMN1; SMN2RAB9ALMNAHPGDMAOB | |
| SCHEMBL1711462 | 0.81 | NOS3 (0.57) | SMN1; SMN2RAB9A | |
| SCHEMBL1711460 | 0.81 | NOS3 (0.57) | SMN1; SMN2RAB9A | |
| SCHEMBL25761086 | 0.80 | MEN1 (0.44) | RAB9ALMNAHPGDMEN1KMT2A | |
| SCHEMBL14244763 | 0.80 | HDAC8 (0.64) | SMN1; SMN2RAB9AMAOBNPC1MAPT | |
| SCHEMBL12425754 | 0.80 | HDAC8 (0.64) | SMN1; SMN2RAB9AMAOBNPC1MAPT | |
| SCHEMBL24449994 | 0.79 | HDAC3 (0.52) | SMN1; SMN2RAB9AGAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274546-A1 | New oxazolinone compounds useful as intermediates for the preparation of insecticidal and acaracidal cinnamide compounds | AMERICAN CYANAMID COMPANY (US) | 1988-07-20 | — | — | EP | disclosed |