Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716936 | 0.98 | NPC1 (0.49) | LMNANPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL20538944 | 0.89 | LMNA (0.43) | LMNASMN1; SMN2CYP3A4MEN1CHRM2 | |
| SCHEMBL2406969 | 0.87 | SMN1; SMN2 (0.50) | LMNANPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL8081132 | 0.86 | SMN1; SMN2 (0.51) | LMNANPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL8081509 | 0.86 | SMN1; SMN2 (0.51) | LMNANPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL5508979 | 0.86 | SMN1; SMN2 (0.51) | LMNANPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL8081523 | 0.86 | SMN1; SMN2 (0.51) | LMNANPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL8072241 | 0.86 | SMN1; SMN2 (0.51) | LMNANPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL10639062 | 0.86 | SMN1; SMN2 (0.51) | LMNANPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL7556093 | 0.84 | GLS (0.43) | LMNASMN1; SMN2MEN1SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |