Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698580 | 0.98 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2MMP9MMP8 | |
| SCHEMBL5508979 | 0.88 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL8081132 | 0.88 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL8072241 | 0.88 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL8081523 | 0.88 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL10639062 | 0.88 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL8081509 | 0.88 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL20538944 | 0.87 | LMNA (0.43) | SMN1; SMN2LMNACYP3A4MEN1CHRM2 | |
| SCHEMBL2406969 | 0.86 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL9999772 | 0.84 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009561-A1 | NEW AMIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-06-11 | — | — | WO | disclosed |