Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812355 | 0.82 | KMT2A (0.47) | KDM4ETDP1KMT2AOPRK1CCR1 | |
| SCHEMBL28248381 | 0.79 | NOS3 (0.37) | KDM4ETDP1CCR1CCR5RAB9A | |
| SCHEMBL1562545 | 0.76 | KMT2A (0.60) | KDM4ETDP1KMT2AOPRK1CCR1 | |
| SCHEMBL24207472 | 0.76 | CCR1 (0.40) | KDM4ETDP1KMT2AOPRK1CCR1 | |
| SCHEMBL20838482 | 0.74 | MAPT (0.49) | KDM4ETDP1KMT2AOPRK1CCR1 | |
| SCHEMBL24446496 | 0.74 | KMT2A (0.41) | KDM4ETDP1KMT2AOPRK1CCR1 | |
| SCHEMBL12258321 | 0.74 | CCR1 (0.57) | KDM4EKMT2AOPRK1CCR1CCR5 | |
| SCHEMBL878950 | 0.74 | OPRK1 (0.52) | KDM4ETDP1KMT2AOPRK1CCR1 | |
| SCHEMBL11559049 | 0.72 | KMT2A (0.50) | KDM4ETDP1KMT2AOPRK1CCR1 | |
| SCHEMBL5447339 | 0.72 | HSP90AA1 (0.59) | KMT2ACCR1CCR8MAPTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282893-A2 | Pesticides based on 1,10-phenanthrolines | BAYER AG (DE) | 1988-09-21 | — | — | EP | disclosed |