Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069879 | 1.00 | LMNA (0.49) | LMNAKMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL18544009 | 0.89 | FURIN (0.43) | LMNAKMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL4112405 | 0.83 | LMNA (0.50) | LMNAKMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL4112402 | 0.83 | LMNA (0.50) | LMNAKMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL18489441 | 0.83 | LMNA (0.50) | LMNAKMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL1638478 | 0.82 | NPC1 (0.48) | CYP1A2CYP3A4SLC6A2L3MBTL1ALDH1A1 | |
| SCHEMBL21113634 | 0.82 | KMT2A (0.43) | LMNAKMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL12726482 | 0.82 | NPC1 (0.48) | CYP1A2CYP3A4SLC6A2L3MBTL1ALDH1A1 | |
| SCHEMBL1638479 | 0.82 | NPC1 (0.48) | CYP1A2CYP3A4SLC6A2L3MBTL1ALDH1A1 | |
| SCHEMBL2155169 | 0.80 | KMT2A (0.50) | LMNAKMT2AGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861409-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-7776980-B2 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20090018292-A1 | Monocyclopentadienyl Complexes | BASELL POLYOLEFINE GMBH (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-1861409-A1 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006100004-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018292-A1 | Monocyclopentadienyl Complexes | TKT, KMO, PKM | LMNA 3093/4885KMT2A 1095/4885GABRA1 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.