Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 18/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 14/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 14/20 | 0.50 |
| ▸ | GABRP | O00591 | 10/20 | 0.50 |
| ▸ | GABRD | O14764 | 10/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.50 |
| ▸ | GABRE | P78334 | 10/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976717 | 0.85 | GABRB3 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14996612 | 0.84 | MAPT (0.48) | — | |
| SCHEMBL14996596 | 0.84 | STIM1 (0.43) | — | |
| SCHEMBL14996611 | 0.83 | GABRB3 (0.52) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL27772986 | 0.83 | GABRB3 (0.49) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14996572 | 0.82 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6962955 | 0.81 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL28833070 | 0.80 | GABRB3 (0.72) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14996685 | 0.79 | GAA (0.53) | — | |
| SCHEMBL7713254 | 0.78 | BACE1 (0.61) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286968-A2 | Substituted 1-arylpyrazoles | BAYER AG (DE) | 1988-10-19 | — | — | EP | disclosed |