Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 18/20 | 0.65 |
| ▸ | GABRP | O00591 | 15/20 | 0.65 |
| ▸ | GABRD | O14764 | 15/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 15/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 15/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.65 |
| ▸ | GABRE | P78334 | 15/20 | 0.65 |
| ▸ | GABRA6 | Q16445 | 15/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 15/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 15/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 15/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562514 | 0.89 | GABRA2 (0.64) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7707146 | 0.87 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7711657 | 0.85 | GABRB3 (0.67) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7713221 | 0.84 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6168749 | 0.83 | GABRB3 (0.68) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10698854 | 0.81 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL239495 | 0.80 | GABRB3 (0.60) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Ammonia Solution, Strong SCHEMBL8425567 | 0.79 | GABRB3 (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6054602 | 0.79 | GABRB3 (0.63) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2553908 | 0.79 | GABRB3 (0.59) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331222-A1 | Environment friendly reagents and process for halogenoalkylsulfinylation of organic compounds | VIRBAC S.A. (FR) | 2003-07-30 | — | — | EP | claimed |
| EP-1331222-A1 | Environment friendly reagents and process for halogenoalkylsulfinylation of organic compounds | VIRBAC S.A. (FR) | 2003-07-30 | — | — | EP | disclosed |
| EP-0946515-B1 | PARASITICIDAL PYRAZOLES | PFIZER LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-6372774-B1 | THESE COMPOUNDS POSSESS ARTHROPODICIDAL, PLANT NEMATOCIDAL, ANTHELMINTIC AND ANTI-PROTOZOAL PROPERTIES | RHONE-POULENC AGRICULTURE LTD. (GB) | 2002-04-16 | — | — | US | disclosed |
| EP-0871617-B1 | PARASITICIDAL COMPOUNDS | PFIZER (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6268509-B1 | PESTICIDES | PFIZER INC | 2001-07-31 | — | — | US | disclosed |
| US-6255333-B1 | HUMANS OR ANIMALS | PFIZER INC. | 2001-07-03 | — | — | US | disclosed |
| US-6075043-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-06-13 | — | — | US | disclosed |
| EP-0946515-A1 | PARASITICIDAL PYRAZOLES | Pfizer Limited (GB) | 1999-10-06 | — | — | EP | disclosed |
| US-5916618-A | PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-06-29 | — | — | US | disclosed |
| WO-1998024767-A1 | PARASITICIDAL PYRAZOLES | PFIZER LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | disclosed |
| US-5608077-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-03-04 | — | — | US | disclosed |
| US-5547974-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0579280-A1 | Pesticidal method using N-phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1994-01-19 | — | — | EP | disclosed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | disclosed |
| EP-0234119-A1 | Pesticidal method using N-phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987003781-A1 | PESTICIDAL METHOD USING N-PHENYLPYRAZOLES | MAY & BAKER LIMITED (GB) | 1987-07-02 | — | — | WO | disclosed |