Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.72 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.72 |
| ▸ | GABRB2 | P47870 | 18/20 | 0.72 |
| ▸ | GABRP | O00591 | 16/20 | 0.72 |
| ▸ | GABRD | O14764 | 16/20 | 0.72 |
| ▸ | GABRA1 | P14867 | 16/20 | 0.72 |
| ▸ | GABRB1 | P18505 | 16/20 | 0.72 |
| ▸ | GABRG2 | P18507 | 16/20 | 0.72 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.72 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.72 |
| ▸ | GABRA4 | P48169 | 16/20 | 0.72 |
| ▸ | GABRE | P78334 | 16/20 | 0.72 |
| ▸ | GABRA6 | Q16445 | 16/20 | 0.72 |
| ▸ | GABRG1 | Q8N1C3 | 16/20 | 0.72 |
| ▸ | GABRG3 | Q99928 | 16/20 | 0.72 |
| ▸ | GABRQ | Q9UN88 | 16/20 | 0.72 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976717 | 0.81 | GABRB3 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10698854 | 0.80 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL27772986 | 0.79 | GABRB3 (0.49) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14996611 | 0.79 | GABRB3 (0.52) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9768161 | 0.73 | GABRB3 (0.57) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7713492 | 0.73 | GABRP (0.66) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7967758 | 0.73 | GABRP (0.78) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL15287105 | 0.73 | GABRB3 (0.52) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9768186 | 0.72 | GABRP (0.57) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6927865 | 0.71 | GABRP (1.00) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483260-B | 1-aryl-5-alkylpyrazole derivative compounds, methods of making and methods of use thereof | 梅瑞尔公司 | 2016-08-03 | — | — | CN | disclosed |