SCHEMBL10699263

SCHEMBL10699263

CCCC(CC)(c1ccc(O)cc1)c1ccc(O)cc1.c1cc2cc-2c1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 16/20 0.65
ESR2 Q92731 9/20 0.65
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
AR P10275 2/20 0.46
ABL1 P00519 1/20 0.42
ABCB1 P08183 1/20 0.42
BCR P11274 1/20 0.42
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1334149 0.88 ESR1 (0.83) ESR1ESR2AR
SCHEMBL4455629 0.81 ESR1 (0.78) ESR1ESR2AR
SCHEMBL272801 0.80 ESR1 (1.00) ESR1ESR2AR
SCHEMBL28036387 0.77 ESR1 (0.84) ESR1ESR2AR
SCHEMBL6562079 0.77 ESR1 (0.85) ESR1ESR2AR
SCHEMBL258649 0.75 ESR1 (1.00) ESR1ESR2AR
SCHEMBL6561210 0.75 ESR1 (0.75) ESR1ESR2AR
SCHEMBL9817091 0.74 ESR1 (0.51) ESR1ESR2AR
SCHEMBL4455627 0.74 ESR1 (0.70) ESR1ESR2AR
SCHEMBL15987572 0.74 ESR1 (0.72) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed