Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143058 | 0.89 | TSHR (0.39) | TSHRALDH1A1ZDHHC20ZDHHC2FAAH | |
| SCHEMBL7536200 | 0.86 | TSHR (0.37) | TSHRALDH1A1ZDHHC20ZDHHC2CYP4F2 | |
| SCHEMBL28966830 | 0.86 | ZDHHC20 (0.42) | TSHRALDH1A1ZDHHC20ZDHHC2FAAH | |
| SCHEMBL11415107 | 0.83 | CYP4F2 (0.35) | TSHRALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL11415097 | 0.83 | ALDH1A1 (0.38) | TSHRALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL16414305 | 0.82 | ZDHHC20 (0.42) | TSHRALDH1A1ZDHHC20ZDHHC2FAAH | |
| SCHEMBL2143415 | 0.82 | ZDHHC20 (0.42) | TSHRALDH1A1ZDHHC20ZDHHC2FAAH | |
| SCHEMBL1703002 | 0.82 | ZDHHC20 (0.42) | TSHRALDH1A1ZDHHC20ZDHHC2FAAH | |
| SCHEMBL11423751 | 0.80 | SMN1; SMN2 (0.44) | TSHRALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL17451110 | 0.80 | CYP4F2 (0.43) | TSHRALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772658-A | ADDITION POLYMERIZATION, POLYISOCYANATE-UNSATURATED ALCOHOL ADDUCT, POLYURETHANES, MOLDINGS | THE DOW CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |