Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700071 | 0.82 | POLB (0.37) | BRD4MEN1KMT2AATMPOLB | |
| SCHEMBL8597022 | 0.76 | ATM (0.42) | MEN1KMT2AATMCCKBRPOLB | |
| SCHEMBL7828421 | 0.76 | ATM (0.42) | MEN1KMT2AATMCCKBRPOLB | |
| SCHEMBL11423317 | 0.76 | MAPT (0.39) | MEN1KMT2AATMCCKBRPOLB | |
| SCHEMBL11423312 | 0.76 | MAPT (0.39) | MEN1KMT2AATMCCKBRPOLB | |
| Water SCHEMBL8600954 | 0.75 | ATM (0.42) | MEN1KMT2AATMCCKBRPOLB | |
| SCHEMBL10401867 | 0.74 | TSHR (0.34) | POLBHDAC1HDAC2LMNA | |
| SCHEMBL16019029 | 0.73 | ATM (0.40) | MEN1KMT2AATMCCKBRHDAC4 | |
| SCHEMBL10700196 | 0.73 | TSHR (0.36) | MEN1KMT2AATMCCKBRPOLB | |
| SCHEMBL10701353 | 0.73 | ALDH1A1 (0.41) | MEN1KMT2AMAPK1POLBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | disclosed |