Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700071 | 0.82 | POLB (0.37) | MEN1KMT2APOLBGAAATM | |
| SCHEMBL11607315 | 0.81 | MEN1 (0.41) | MEN1KMT2ACCKBRPOLBLMNA | |
| SCHEMBL10401867 | 0.77 | TSHR (0.34) | TSHRPOLBTOP1LMNAKDM4E | |
| SCHEMBL10700121 | 0.73 | BRD4 (0.36) | MEN1KMT2ACCKBRPOLBLMNA | |
| SCHEMBL11605827 | 0.73 | KMT2A (0.42) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL10702187 | 0.72 | LMNA (0.35) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL10402768 | 0.72 | CACNA2D1 (0.41) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10437840 | 0.71 | TOP1 (0.59) | TSHRTOP1KDM4EALDH1A1GAA | |
| SCHEMBL11733894 | 0.71 | KMT2A (0.42) | MEN1KMT2ACCKBRLMNAALDH1A1 | |
| SCHEMBL7828421 | 0.70 | ATM (0.42) | TSHRMEN1KMT2ACCKBRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | disclosed |