Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730042 | 0.81 | MAPT (0.61) | CDC25ACDC25BALDH1A1FGFR1FGFR2 | |
| SCHEMBL5138652 | 0.81 | CDC25B (0.58) | CDC25ACDC25BALDH1A1FGFR1FGFR2 | |
| SCHEMBL5138007 | 0.81 | CDC25A (0.40) | CDC25ACDC25BALDH1A1FGFR1FGFR2 | |
| SCHEMBL7107949 | 0.80 | MAPT (0.37) | CDC25ACDC25BALDH1A1FGFR1FGFR2 | |
| SCHEMBL4590579 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTMITFHTTNPSR1 | |
| SCHEMBL19879495 | 0.77 | ALDH1A1 (0.50) | CDC25ACDC25BALDH1A1FGFR1FGFR2 | |
| SCHEMBL9068235 | 0.73 | TSHR (0.47) | CDC25ACDC25BALDH1A1MAPTHTT | |
| SCHEMBL9695242 | 0.72 | MAPT (0.61) | CDC25ACDC25BALDH1A1FGFR1FGFR2 | |
| SCHEMBL9359484 | 0.70 | ALDH1A1 (0.42) | CDC25ACDC25BALDH1A1MAPTMITF | |
| SCHEMBL532969 | 0.69 | ALDH1A1 (0.67) | ALDH1A1MAPTHTTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251357-A1 | Engineering thermoplastics containing pendant benzocyclobutene groups | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-01-07 | — | — | EP | disclosed |