Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.58 |
| ▸ | CDC25A | P30304 | 2/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.55 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.55 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.55 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695242 | 0.91 | MAPT (0.61) | CDC25BCDC25AFGFR1FGFR2FGFR4 | |
| SCHEMBL15730042 | 0.83 | MAPT (0.61) | CDC25BCDC25AFGFR1FGFR2FGFR4 | |
| SCHEMBL20121190 | 0.81 | PDE4B (0.54) | CDC25BCDC25AFGFR1FGFR2FGFR4 | |
| SCHEMBL7258464 | 0.81 | PDE4B (0.54) | CDC25BCDC25AFGFR1FGFR2FGFR4 | |
| SCHEMBL10700253 | 0.81 | CDC25A (0.45) | CDC25BCDC25AFGFR1FGFR2FGFR4 | |
| SCHEMBL1556617 | 0.81 | CDC25B (0.60) | CDC25BCDC25AMAPTALDH1A1NPSR1 | |
| SCHEMBL740371 | 0.79 | FGFR1 (0.61) | CDC25BCDC25AFGFR1FGFR2FGFR4 | |
| SCHEMBL17969766 | 0.79 | CDC25B (0.58) | CDC25BCDC25AMAPTALDH1A1NPSR1 | |
| SCHEMBL5497788 | 0.79 | MAPT (0.65) | CDC25BCDC25AFGFR1FGFR2FGFR4 | |
| SCHEMBL29941466 | 0.78 | CDC25B (0.68) | CDC25BCDC25AMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |
| US-4151182-A | CATALYTIC OXIDATION FROM INDANS OR DIPHENYLMETHANE DERIVATIVES | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) | 1979-04-24 | — | — | US | disclosed |