SCHEMBL10700330

SCHEMBL10700330

O=C1C=C(NCc2ccccc2)C(=NS(=O)(=O)c2ccccc2)C=C1NCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.52
NSD2 O96028 7/20 0.52
POLB P06746 7/20 0.52
MEN1 O00255 7/20 0.52
MAPT P10636 4/20 0.52
BLM P54132 4/20 0.52
HKDC1 Q2TB90 4/20 0.52
LMNA P02545 3/20 0.52
GALK1 P51570 3/20 0.52
ALDH1A1 P00352 3/20 0.52
RAB9A P51151 3/20 0.52
THRB P10828 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
KDM4E B2RXH2 1/20 0.52
PLEC Q15149 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
APAF1 O14727 7/20 0.46
MAPK1 P28482 2/20 0.42
GAA P10253 1/20 0.42
HSP90AA1 P07900 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2556802 0.80 MEN1 (0.70) KMT2ANSD2POLBMEN1MAPT
SCHEMBL27840721 0.71 POLB (0.57) KMT2ANSD2POLBMEN1MAPT
SCHEMBL10195778 0.69 MAPT (1.00) KMT2ANSD2POLBMEN1MAPT
SCHEMBL15690641 0.68 MAPT (0.78) KMT2ANSD2POLBMEN1MAPT
SCHEMBL30991482 0.68 MAPT (0.78) KMT2ANSD2POLBMEN1MAPT
SCHEMBL9334488 0.67 MEN1 (0.61) KMT2ANSD2POLBMEN1MAPT
SCHEMBL14571428 0.64 KMT2A (0.71) KMT2ANSD2POLBMEN1MAPT
SCHEMBL14189448 0.64 MEN1 (0.49) KMT2ANSD2POLBMEN1MAPT
SCHEMBL10719073 0.64 MEN1 (0.56) KMT2ANSD2POLBMEN1MAPT
SCHEMBL19409867 0.63 LMNA (0.47) KMT2ANSD2POLBMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253219-A2 Photoresist compositions containing quinone sensitizer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-01-20 EP disclosed
US-4684599-A POSITIVE-WORKING, ALKALI SOLUBILITY EASTMAN KODAK COMPANY (US) 1987-08-04 US disclosed