Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NSD2 | O96028 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | GALK1 | P51570 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PLEC | Q15149 | 1/20 | 0.70 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10195778 | 0.83 | MAPT (1.00) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL15690641 | 0.81 | MAPT (0.78) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL30991482 | 0.81 | MAPT (0.78) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL9334488 | 0.80 | MEN1 (0.61) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL10700330 | 0.80 | KMT2A (0.52) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL19409867 | 0.79 | LMNA (0.47) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL2553876 | 0.77 | LTA4H (0.57) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL10719073 | 0.76 | MEN1 (0.56) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL19409871 | 0.75 | FFAR1 (0.48) | MEN1KMT2APOLBTHRBKDM4E | |
| SCHEMBL28378249 | 0.74 | LMNA (0.57) | MEN1KMT2APOLBTHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011126544-A2 | THYMOQUINONE ANALOGS FOR THE TREATMENT OF PANCREATIC CANCER | WAYNE STATE UNIVERSITY (US) | 2011-10-13 | — | — | WO | claimed |
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2017-10-05 | — | — | US | disclosed |
| WO-2011126544-A2 | THYMOQUINONE ANALOGS FOR THE TREATMENT OF PANCREATIC CANCER | WAYNE STATE UNIVERSITY (US) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | BRCA1, BBOX1, KMO | MEN1 863/4885KMT2A 184/4885POLB 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.