Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | NSD2 | O96028 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | GALK1 | P51570 | 1/20 | 1.00 |
| ▸ | PLEC | Q15149 | 1/20 | 1.00 |
| ▸ | APAF1 | O14727 | 5/20 | 0.59 |
| ▸ | CASP3 | P42574 | 5/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690641 | 0.88 | MAPT (0.78) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL30991482 | 0.88 | MAPT (0.78) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL2556802 | 0.83 | MEN1 (0.70) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL15690511 | 0.77 | MAPT (0.62) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL9334488 | 0.76 | MEN1 (0.61) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL15700128 | 0.76 | ALDH1A1 (0.60) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL15700149 | 0.76 | MAPT (0.60) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL6409344 | 0.74 | MAPT (1.00) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL30587682 | 0.74 | MAPT (1.00) | MAPTKMT2ALMNABLMKDM4E | |
| SCHEMBL29226600 | 0.74 | RAB9A (0.58) | MAPTKMT2ALMNABLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
| WO-2012006104-A2 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | Academia Sinica, Taiwan (TW) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | TALDO1, PGD, DLD | MAPT 3251/4885KMT2A 2118/4885LMNA 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.