Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18387854 | 0.85 | HTR2A (0.47) | CETPHTR2AHTR2BHTR2CNPSR1 | |
| SCHEMBL29193456 | 0.77 | PDE2A (0.42) | CES2MGLLTSHRPDE2A | |
| SCHEMBL15013852 | 0.76 | HTR2A (0.46) | CETPHTR2AHTR2BHTR2CNPSR1 | |
| SCHEMBL23502231 | 0.75 | CES2 (0.48) | CETPNPSR1PNMTMAPTCES2 | |
| SCHEMBL30901511 | 0.75 | TSHR (0.48) | CETPHTR2AHTR2BHTR2CCES2 | |
| SCHEMBL171829 | 0.75 | TSHR (0.48) | CETPHTR2AHTR2BHTR2CCES2 | |
| SCHEMBL7592350 | 0.74 | TSHR (0.52) | CETPHTR2AHTR2BHTR2CNPSR1 | |
| SCHEMBL13152932 | 0.74 | RORC (0.46) | CETPHTR2AHTR2BHTR2CNPSR1 | |
| SCHEMBL13338397 | 0.74 | IDO1 (0.44) | CETPHTR2AHTR2BHTR2CNPSR1 | |
| SCHEMBL28746553 | 0.73 | MLYCD (0.54) | CETPNPSR1MAPTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761502-A | POLYURETHANE INTERMEDIATES, COLORS | MILLIKEN RESEARCH CORPORATION (US) | 1988-08-02 | — | — | US | disclosed |