Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678434 | 0.88 | PDE10A (0.39) | PRMT5WDR77KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10699335 | 0.86 | POLB (0.34) | PRMT5WDR77KDM4ESMN1; SMN2MAPT | |
| SCHEMBL10700842 | 0.85 | CBFB (0.33) | PRMT5WDR77SRCFGFR1KDM4E | |
| SCHEMBL9395685 | 0.85 | SMN1; SMN2 (0.39) | PRMT5WDR77KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9395701 | 0.85 | LMNA (0.45) | PRMT5WDR77ABL1KDM4EALDH1A1 | |
| SCHEMBL6481713 | 0.83 | GAA (0.39) | PRMT5WDR77SRCABL1PLA2G2A | |
| SCHEMBL10711376 | 0.81 | ATP4A (0.40) | KDM4EMAPK1ATP4AATP4BNPC1 | |
| SCHEMBL10700467 | 0.81 | PDE10A (0.36) | KDM4EALDH1A1SMN1; SMN2ATP4AATP4B | |
| SCHEMBL10702652 | 0.80 | OGT (0.37) | ABL1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10698219 | 0.80 | SMN1; SMN2 (0.49) | PRMT5WDR77ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |