Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | CASP1 | P29466 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698891 | 0.89 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL10699249 | 0.87 | HPGD (0.37) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL10696066 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL10698144 | 0.81 | KDM4E (0.39) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL10701683 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4EHPGDCASP1GAA | |
| SCHEMBL10700212 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL10700152 | 0.77 | CA12 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL10700949 | 0.77 | BMPR1B (0.36) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL10699606 | 0.75 | TNKS2 (0.43) | ALDH1A1KDM4EHSD17B10GAAMEN1 | |
| SCHEMBL10700922 | 0.74 | CBFB (0.52) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |