Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699555 | 0.87 | KMT2A (0.75) | KMT2ASMN1; SMN2KDM4EMEN1HTT | |
| SCHEMBL15958914 | 0.85 | KMT2A (0.49) | KMT2ASMN1; SMN2KDM4EMAPK1NPSR1 | |
| SCHEMBL773258 | 0.83 | KMT2A (0.74) | KMT2ASMN1; SMN2KDM4EMAPK1NPSR1 | |
| SCHEMBL28001062 | 0.82 | LMNA (0.53) | KMT2ASMN1; SMN2KDM4EMAPK1NPSR1 | |
| SCHEMBL10486057 | 0.81 | KMT2A (0.51) | KMT2ASMN1; SMN2KDM4EMAPK1NPSR1 | |
| SCHEMBL29620677 | 0.81 | MAPT (0.57) | KMT2ASMN1; SMN2KDM4EMAPK1NPSR1 | |
| SCHEMBL1496603 | 0.80 | CYP1A2 (0.58) | KMT2AMAPK1NPSR1MEN1KCNH2 | |
| Hydrochloric Acid SCHEMBL11137461 | 0.80 | KMT2A (0.54) | KMT2ASMN1; SMN2KDM4EMAPK1NPSR1 | |
| SCHEMBL2835769 | 0.79 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2KDM4EMAPK1NPSR1 | |
| SCHEMBL14282215 | 0.78 | MAPK1 (0.64) | SMN1; SMN2KDM4EMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269383-A2 | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-06-01 | — | — | EP | disclosed |