Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 9/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336360 | 0.86 | KMT2A (0.69) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL29598938 | 0.86 | KMT2A (0.69) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10701351 | 0.82 | KMT2A (0.56) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10701355 | 0.82 | KDM4E (0.51) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL2835769 | 0.81 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL8682006 | 0.81 | PNMT (0.50) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL8682004 | 0.81 | PNMT (0.50) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL5949941 | 0.80 | LMNA (0.78) | LMNASMN1; SMN2KDM4EALDH1A1NPSR1 | |
| SCHEMBL773258 | 0.79 | KMT2A (0.74) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL15011707 | 0.79 | LMNA (0.64) | LMNAKMT2AALDH1A1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |