Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MB | P02144 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9596558 | 0.98 | ALDH1A1 (0.50) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| SCHEMBL10496940 | 0.84 | CACNA1B (0.53) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| SCHEMBL15047897 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9596329 | 0.83 | CACNA1B (0.51) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| SCHEMBL11235456 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| SCHEMBL10496871 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| SCHEMBL10497023 | 0.81 | SLC6A3 (0.55) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10390651 | 0.80 | MEN1 (0.49) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| SCHEMBL10815283 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A | |
| SCHEMBL9821071 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1HTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174242-B1 | 1-(AMINO-PHENYL)-2-AMINO PROPANON DERIVATIVES, THEIR USE IN THERAPY AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1988-01-13 | — | — | EP | disclosed |
| EP-0174242-A2 | 1-(Amino-phenyl)-2-amino propanon derivatives, their use in therapy and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1986-03-12 | — | — | EP | disclosed |