Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SAT1 | P21673 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516926 | 0.95 | ALDH1A1 (0.38) | EPHX1TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL7515767 | 0.82 | — | — | |
| SCHEMBL9820594 | 0.77 | EPHX1 (0.48) | EPHX1ALDH1A1 | |
| SCHEMBL4556954 | 0.75 | EPHX1 (0.57) | EPHX1ALDH1A1 | |
| SCHEMBL2917839 | 0.74 | — | — | |
| SCHEMBL6901082 | 0.74 | — | — | |
| SCHEMBL12846940 | 0.74 | USP2 (0.45) | — | |
| SCHEMBL9820564 | 0.74 | EPHX1 (0.60) | EPHX1ALDH1A1 | |
| SCHEMBL15740339 | 0.74 | USP2 (0.45) | — | |
| SCHEMBL14196079 | 0.74 | USP2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287951-A2 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |