Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 4/20 | 0.52 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10953674 | 0.86 | ANPEP (0.55) | ANPEPMMP9MMP1MMP8MMP3 | |
| SCHEMBL10705718 | 0.86 | ANPEP (0.55) | ANPEPMMP9MMP1MMP8MMP3 | |
| SCHEMBL7306277 | 0.81 | ANPEP (0.64) | ANPEPKMT2AMEN1TSHRMMP9 | |
| SCHEMBL7306287 | 0.81 | ANPEP (0.64) | ANPEPKMT2AMEN1TSHRMMP9 | |
| SCHEMBL10706501 | 0.78 | CA5A (0.60) | MMP9MMP1CA5A | |
| SCHEMBL8255279 | 0.78 | ANPEP (0.80) | ANPEPKMT2AMEN1TSHR | |
| SCHEMBL5870044 | 0.78 | ANPEP (0.80) | ANPEPKMT2AMEN1TSHR | |
| SCHEMBL13073874 | 0.77 | ANPEP (0.63) | ANPEPKMT2AMEN1TSHRMMP8 | |
| SCHEMBL8613610 | 0.77 | ANPEP (0.63) | ANPEPKMT2AMEN1TSHRMMP8 | |
| SCHEMBL18435144 | 0.76 | KMT2A (0.56) | ANPEPKMT2AMEN1TSHRMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126974-B1 | CARBOXYALKYL PEPTIDE DERIVATIVES | G.D. Searle & Co. (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4568666-A | COLLAGENASE INHIBITORS, ANTIARTJRITIC AGENTS | G. D. SEARLE & CO. (US) | 1986-02-04 | — | — | US | disclosed |
| US-4511504-A | COLLAGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1985-04-16 | — | — | US | disclosed |