Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.64 |
| ▸ | MMP3 | P08254 | 3/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 5/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306287 | 1.00 | ANPEP (0.64) | ANPEPMMP3MMP9MMP8CA5A | |
| SCHEMBL7305062 | 0.87 | ANPEP (0.62) | ANPEPMMP9MMP8CA5APSMB1 | |
| SCHEMBL14444053 | 0.81 | MMP8 (0.66) | ANPEPMMP3MMP8KMT2A | |
| SCHEMBL10704435 | 0.81 | ANPEP (0.61) | ANPEPMMP3MMP9MMP8CA5A | |
| SCHEMBL7305439 | 0.80 | LAP3 (0.62) | ANPEPMMP8MEN1KMT2A | |
| SCHEMBL7299705 | 0.80 | CAPN1 (0.56) | ANPEPMMP9MMP8 | |
| SCHEMBL7304649 | 0.80 | CAPN1 (0.56) | ANPEPMMP9MMP8 | |
| SCHEMBL7299696 | 0.80 | CAPN1 (0.56) | ANPEPMMP9MMP8 | |
| SCHEMBL7304634 | 0.80 | CAPN1 (0.56) | ANPEPMMP9MMP8 | |
| SCHEMBL7296586 | 0.79 | CAPN1 (0.58) | MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | claimed |
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |