Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 4/20 | 0.47 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707067 | 0.91 | GCGR (0.53) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10706951 | 0.91 | TDP1 (0.54) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10711361 | 0.89 | GCGR (0.57) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10711033 | 0.89 | LMNA (0.55) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10704619 | 0.87 | GCGR (0.54) | GCGRTDP1PCTPRAB9ANPC1 | |
| Chlorbenzuron SCHEMBL5177776 | 0.86 | GCGR (0.68) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10778835 | 0.83 | TDP1 (0.66) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10711136 | 0.83 | GCGR (0.55) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10705546 | 0.83 | GCGR (0.53) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10705754 | 0.82 | GCGR (0.64) | GCGRTDP1PCTPRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | claimed |
| EP-0116729-B1 | BENZOYLUREA COMPOUNDS AND PESTICIDAL COMPOSITIONS COMPRISINGSAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-10-12 | — | — | EP | disclosed |
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |
| EP-0116729-A2 | Benzoylurea compounds and pesticidal compositions comprisingsame | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-08-29 | — | — | EP | disclosed |