Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 2/20 | 0.44 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707067 | 0.93 | GCGR (0.53) | LMNAGCGRTDP1SLC6A3PCTP | |
| SCHEMBL10705614 | 0.89 | TDP1 (0.53) | LMNATDP1SLC6A3PCTPHPGD | |
| SCHEMBL10704516 | 0.89 | GCGR (0.55) | LMNAGCGRTDP1PCTPRAB9A | |
| SCHEMBL10714234 | 0.89 | LMNA (0.52) | LMNAGCGRTDP1PCTPHPGD | |
| SCHEMBL10706279 | 0.85 | GCGR (0.50) | LMNAGCGRTDP1PCTPHPGD | |
| SCHEMBL10705504 | 0.85 | GCGR (0.49) | LMNAGCGRTDP1PCTPHPGD | |
| SCHEMBL10705546 | 0.84 | GCGR (0.53) | LMNAGCGRTDP1PCTPRAB9A | |
| SCHEMBL10705777 | 0.82 | GCGR (0.48) | LMNAGCGRTDP1PCTPRAB9A | |
| Chlorbenzuron SCHEMBL5177776 | 0.82 | GCGR (0.68) | GCGRTDP1PCTPRAB9ANPC1 | |
| SCHEMBL10712013 | 0.82 | SLC6A3 (0.53) | LMNASLC6A3RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |