Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800847 | 0.89 | TDP1 (0.82) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL10713466 | 0.86 | TDP1 (0.60) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL10710076 | 0.86 | TDP1 (0.77) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL10714350 | 0.85 | TDP1 (0.58) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL10706951 | 0.84 | TDP1 (0.54) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL10704516 | 0.83 | GCGR (0.55) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL515847 | 0.81 | TDP1 (0.80) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL9861823 | 0.81 | TDP1 (0.75) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| SCHEMBL27847099 | 0.80 | TDP1 (0.78) | TDP1RAB9AALDH1A1GCGRNPC1 | |
| Triflumuron SCHEMBL9490691 | 0.80 | TDP1 (1.00) | TDP1RAB9AALDH1A1GCGRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |
| EP-0116729-A2 | Benzoylurea compounds and pesticidal compositions comprisingsame | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-08-29 | — | — | EP | disclosed |