Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807438 | 0.89 | TSHR (0.50) | FLT1FLT4KDRTSHRCASP1 | |
| SCHEMBL9592939 | 0.82 | MEN1 (0.49) | FLT1FLT4KDRTSHRCASP1 | |
| SCHEMBL28668332 | 0.81 | SMN1; SMN2 (0.52) | FLT1FLT4KDRTSHRCASP1 | |
| SCHEMBL611648 | 0.79 | SRD5A2 (0.70) | FLT1FLT4KDRTSHRCASP1 | |
| SCHEMBL9592286 | 0.79 | TSHR (0.44) | TSHRCASP1SMN1; SMN2SRD5A2MAPT | |
| SCHEMBL10705376 | 0.78 | HTT (0.46) | TSHRSMN1; SMN2CYP3A4MAPTRAB9A | |
| SCHEMBL10389925 | 0.78 | HSD11B1 (0.46) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL10905142 | 0.75 | CA1 (0.42) | TSHRCASP1SMN1; SMN2SRD5A2CYP3A4 | |
| SCHEMBL21362581 | 0.72 | ANO1 (0.40) | SMN1; SMN2RAB9ANPC1GABRA1GABRB1 | |
| SCHEMBL2081053 | 0.72 | TSHR (0.48) | FLT1FLT4KDRTSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066943-B1 | 1,1-DIPHENYLALKENES AND A PROCESS FOR THEIR PREPARATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | claimed |
| EP-0066943-A1 | 1,1-Diphenylalkenes and a process for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-15 | — | — | EP | claimed |